Sam Kean

The periodic table of the elements is a crowning scientific achievement, but it's also a treasure trove of passion, adventure, obsession, and betrayal. These tales follow carbon, neon, silicon, gold, and all the elements in the table as they play out their parts in human history. The usual suspects are here, like Marie Curie (and her radioactive journey to the discovery of polonium and radium) and William Shockley (who is credited, not exactly justly,...

"In The Disappearing Spoon, bestselling author Sam Kean unlocked the mysteries of the periodic table. In THE VIOLINIST'S THUMB, he explores the wonders of the magical building block of life: DNA. There are genes to explain crazy cat ladies, why other people have no fingerprints, and why some people survive nuclear bombs. Genes illuminate everything from JFK's bronze skin (it wasn't a tan) to Einstein's genius. They prove that Neanderthals and humans...

"Science is a force for good in the world--at least usually. But sometimes, when obsession gets the better of scientists, they twist a noble pursuit into something sinister. Under this spell, knowledge isn't everything, it's the only thing--no matter the cost. Bestselling author Sam Kean tells the true story of what happens when unfettered ambition pushes otherwise rational men and women to cross the line in the name of science, trampling ethical...

A young readers edition of the New York Times bestseller The Disappearing Spoon, chronicling the extraordinary stories behind one of the greatest scientific tools in existence: the periodic table.
Why did Gandhi hate iodine (I, 53)? How did radium (Ra, 88) nearly ruin Marie Curie's reputation? And why did tellurium (Te, 52) lead to the most bizarre gold rush in history?
The periodic table is a crowning scientific achievement,...

Because DNA is only a blueprint, the discovery of its double helix structure was just the beginning. Trace the next big step: understanding how DNA synthesizes proteins through the intermediary of RNA. Here again, a dark horse researcher (Marshall Nirenberg) made the crucial breakthrough. Then see how DNA fingerprinting became possible in the 1980s.

Enter the home stretch in the race to find the structure of DNA. With eminent chemist Linus Pauling leading the pack, longshots James Watson and Francis Crick got a key clue from rival investigator Rosalind Franklin (without her knowledge). Analyze the reasoning that led Watson and Crick to their 1953 breakthrough, and consider why Franklin didn't beat them to it.

Every cell in the human body has essentially the same DNA, yet cells behave very differently, partly due to epigenetics. In epigenetics, the DNA genetic sequence remains constant, but the activity of that sequence changes as genes get switched on and off. More surprising, epigenetics also explains how the inheritance of traits can be influenced by environmental factors.

Investigate the first precision technique for genetic engineering, CRISPR, heralded as holding the potential for science fiction-like manipulation of the human genome. Trace the history of CRISPR-based techniques from a coastal salt marsh, to the fight over patents. Consider the potential for abuse of this powerful tool.

Cover the "Manhattan Project" of DNA: the Human Genome Project to sequence all three billion base pairs of human genetic material. Two separate teams, led by Francis Collins and Craig Venter, competed bitterly to reach this costly goal, which required new technologies and controversial methods. Examine the politics and unexpected legacy of this effort, which was declared complete in 2003.

In the wake of the Human Genome Project, scientists were able to chart our shared heritage with a multitude of species. Most startling was evidence of breeding between modern humans and Neanderthals in the deep past, with a small percentage of Neanderthal DNA present in major human populations today. Peer into the human genome to read these and other clues about our multifaceted history.